灵敏度：2.67 pg/ml (range 62.5 – 2,000 pg/ml)测定时间：3小时应用：用于人、小鼠和大鼠细胞裂解液中[pThr202/Tyr204]Erk1/2 的测定。交叉反应：Phospho Erk (100%) and <0.01%: non-phosphorylated Erk, phospho p38, non-phosphorylated p38, phospho Jnk, non-phosphorylated Jnk, phospho AKT and non-phosphorylated AKT 试剂盒包含：Microtiter plate, Conjugate, Antibody, Assay buffer 21, Wash buffer concentrate, Standard, TMB Substrate, RIPA Cell lysis buffer 2, Stop solution 2其它参数：The mitogen-activated protein kinase (MAPK) pathway exists in all eukaryotes. It consists of several subgroups including ERK 1/2 (extracellular signal-regulated kinase), JNK and p38 kinases. These kinases regulate and control fundamental cellular processes including proliferation, apoptosis, survival and differentiation. They are activated by diverse stimuli including cytokines, growth factors, irradiation, changes in osmolarity, heat and shear stress. MAP kinases are characterized by their requirement for dual phosphorylation for full activation. ERK1 (44kDa) and ERK2 (42kDa) kinases are characterized by their requirement for dual phosphorylation at a conserved T-E-Y motif. The literature contains numerous and extensive reviews on MAP kinase.